A Computational-Based Method for Predicting Drug–Target Interactions by Using Stacked Autoencoder Deep Neural Network

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A conjugate gradient based method for Decision Neural Network training

Decision Neural Network is a new approach for solving multi-objective decision-making problems based on artificial neural networks. Using inaccurate evaluation data, network training has improved and the number of educational data sets has decreased. The available training method is based on the gradient decent method (BP). One of its limitations is related to its convergence speed. Therefore,...

متن کامل

Deep Dictionary Learning vs Deep Belief Network vs Stacked Autoencoder: An Empirical Analysis

A recent work introduced the concept of deep dictionary learning. The first level is a dictionary learning stage where the inputs are the training data and the outputs are the dictionary and learned coefficients. In subsequent levels of deep dictionary learning, the learned coefficients from the previous level acts as inputs. This is an unsupervised representation learning technique. In this wo...

متن کامل

Deep neural network-based bottleneck feature and denoising autoencoder-based dereverberation for distant-talking speaker identification

Deep neural network (DNN)-based approaches have been shown to be effective in many automatic speech recognition systems. However, few works have focused on DNNs for distant-talking speaker recognition. In this study, a bottleneck feature derived from a DNN and a cepstral domain denoising autoencoder (DAE)-based dereverberation are presented for distant-talking speaker identification, and a comb...

متن کامل

Stacked Robust Autoencoder for Classification

In this work we propose an lp-norm data fidelity constraint for training the autoencoder. Usually the Euclidean distance is used for this purpose; we generalize the l2-norm to the lp-norm; smaller values of p make the problem robust to outliers. The ensuing optimization problem is solved using the Augmented Lagrangian approach. The proposed lp -norm Autoencoder has been tested on benchmark deep...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Computational Biology

سال: 2018

ISSN: 1557-8666

DOI: 10.1089/cmb.2017.0135